Choo Hock Tan Selected Research

Venoms

5/2023	Characterizing and applying immunoglobulins in snakebite diagnostics: A simple and rapid venom detection assay for four medically important snake species in Southeast Asia.
1/2023	An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms.
3/2022	Varespladib (LY315920) rescued mice from fatal neurotoxicity caused by venoms of five major Asiatic kraits (Bungarus spp.) in an experimental envenoming and rescue model.
12/2021	Capillary leak syndrome induced by the venoms of Russell's Vipers (Daboia russelii and Daboia siamensis) from eight locales and neutralization of the differential toxicity by three snake antivenoms.
1/2021	King Cobra and snakebite envenomation: on the natural history, human-snake relationship and medical importance of Ophiophagus hannah.
10/2020	Toxicity and cross-neutralization of snake venoms from two lesser-known arboreal pit vipers in Southeast Asia: Trimeresurus wiroti and Trimeresurus puniceus.
7/2020	Comparative venom proteomics of banded krait (Bungarus fasciatus) from five geographical locales: Correlation of venom lethality, immunoreactivity and antivenom neutralization.
1/2020	Cytotoxicity of Snake Venoms and Cytotoxins From Two Southeast Asian Cobras (Naja sumatrana, Naja kaouthia): Exploration of Anticancer Potential, Selectivity, and Cell Death Mechanism.
1/2020	Proteomics and antivenom immunoprofiling of Russell's viper (Daboia siamensis) venoms from Thailand and Indonesia.
1/2020	Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (Trimeresurus purpureomaculatus) venom and its disintegrin (purpureomaculin).

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Choo Hock Tan Research Topics

Disease

16	Snake Bites (Snake Bite) 05/2023 - 02/2011
8	Paralysis (Palsy) 01/2023 - 10/2015
7	Bites and Stings (Sting) 01/2021 - 02/2011
4	Type V Distal Hereditary Motor Neuronopathy 12/2021 - 01/2018
3	Hypersensitivity (Allergy) 01/2023 - 11/2016
2	Thrombocytopenia (Thrombopenia) 01/2023 - 10/2016
2	Necrosis 10/2022 - 01/2020
2	Hemorrhage 12/2021 - 10/2016
2	Neglected Diseases 01/2021 - 01/2020
2	Neoplasms (Cancer) 01/2020 - 01/2020
2	Myotoxicity 10/2019 - 01/2016
2	Pain (Aches) 10/2019 - 01/2017
2	Acute Kidney Injury (Acute Renal Failure) 12/2012 - 02/2011
1	Airway Obstruction (Choking) 03/2022
1	Asphyxia (Suffocation) 03/2022
1	Respiratory Paralysis 03/2022
1	Capillary Leak Syndrome 12/2021
1	Breast Neoplasms (Breast Cancer) 01/2020
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Abdominal Pain (Pain, Abdominal) 01/2017
1	Inflammation (Inflammations) 10/2015
1	Hematuria 04/2014
1	Proteinuria 04/2014

Drug/Important Bio-Agent (IBA)

25	VenomsIBA 05/2023 - 02/2011
18	Antivenins (Antivenoms)IBA 01/2023 - 02/2011
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2017
4	NeurotoxinsIBA 01/2023 - 10/2015
3	Elapid Venoms (Cobra Venom)IBA 09/2022 - 02/2015
3	Snake Venoms (Snake Venom)IBA 12/2021 - 10/2015
3	Cytotoxins (Cytolysins)IBA 01/2020 - 01/2016
2	rhodocetinIBA 01/2023 - 10/2016
2	AlbuminsIBA 01/2023 - 11/2016
2	Phospholipases A2 (Phospholipase A2)IBA 03/2022 - 01/2016
2	ProteomeIBA 01/2021 - 01/2017
2	EnzymesIBA 01/2020 - 10/2015
2	Three Finger ToxinsIBA 01/2019 - 10/2015
1	AntibodiesIBA 05/2023
1	Immunoglobulins (Immunoglobulin)IBA 05/2023
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2023
1	Transferrin (beta 2 Transferrin)IBA 01/2023
1	Fibrinogen (Factor I)FDA Link 01/2023
1	PlasminogenIBA 01/2023
1	Fibronectins (Fibronectin)IBA 01/2023
1	varespladibIBA 03/2022
1	PLIalphaIBA 03/2022
1	Bungarotoxins (alpha-Bungarotoxin)IBA 03/2022
1	SolutionsIBA 07/2020
1	ImmunosorbentsIBA 01/2020
1	CaspasesIBA 01/2020
1	Creatine Kinase (Creatine Phosphokinase)IBA 10/2019
1	Neuromuscular Blocking AgentsIBA 01/2018
1	Cholinergic Agents (Cholinergics)IBA 01/2017
1	Hemolytic AgentsIBA 10/2016
1	Ancrod (Arvin)IBA 10/2016
1	CreatinineIBA 12/2012
1	Urea (Carbamide)FDA LinkGeneric 12/2012
1	Hemostatics (Antihemorrhagics)IBA 02/2011

Therapy/Procedure

1	Therapeutics 01/2020
1	Analgesia 10/2019